According to Saudi Gazette, Uzbekistan's health ministry has
said that 18 children have died after drinking a cough syrup manufactured by
Indian drug maker Marion Biotech.
The ministry said that preliminary tests showed a batch of
the medicine contained ethylene glycol, a toxic substance.
The children were given the Dok-1 Max syrup without a
doctor's prescription, it said. The amount they consumed also exceeded the
standard dose for children.
The allegation from Uzbekistan comes weeks after The Gambia
also linked child deaths to cough syrups made by another Indian firm.
India's health ministry said in a statement that its
officials have been in regular contact with the national drug regulator of
Uzbekistan regarding the matter since December 27, 2022.
It added that health officials have conducted an inspection
of Marion Biotech's facility in Noida in Uttar Pradesh state.
"The samples of the cough syrup have been taken from
the manufacturing premises and sent to Regional Drugs Testing Laboratory,
Chandigarh for testing," the statement added.
News agency ANI has quoted a Marion Biotech executive as
saying that the company has halted production of the syrup temporarily. He
added that the government was conducting an enquiry and that the firm would
take action accordingly.
Marion Biotech is based in Noida, near India's national
capital Delhi. Its website is currently down, but the company's LinkedIn page
says it was founded in 1999 and that its products are household names in
Central Asian countries, Central and Latin America, South East Asia and
Africa".
India produces a third of the world's medicines, mostly in
the form of generic drugs.
The country, home to some of the fastest-growing pharmaceutical
companies, is known as the world's pharmacy and meets much of the medical needs
of developing countries.
The Uzbek ministry statement, dated December 27, says that
Dok-1 Max tablets and syrup have been sold in the country since 2012.
"It was found that the deceased children, before
admission to hospital treatment, took this drug at home for 2-7 days, 3-4 times
a day, 2.5-5ml, which exceeds the standard dose of the drug for children,"
the ministry said.
The statement did not specify over what time period the
deaths occurred. BBC Monitoring had reported on December 23, citing news
website Gazeta.uz, that Uzbek authorities were investigating claims that 15
children died in central Samarkand region over the past two months after taking
a cough syrup made in India".
On December 26, Podrobno.uz news website reported that 21
children - 15 of them under the age of three - were treated for acute kidney
failure allegedly caused by the India-made cough syrup Dok-1 Max between
September and December". Three of the patients recovered.
The ministry also said that preliminary laboratory studies
have shown that this series of Dok-1 Max syrup contains ethylene glycol.
In
October 2022, the World Health Organization (WHO) had sounded a global alert
and linked four India-made cough syrups to the deaths of 66 children from
kidney injuries in The Gambia. It said tests on samples of the syrup showed
that they contained unacceptable amounts of toxic substances diethylene glycol
and ethylene glycol.
Both the Indian government and the company, Maiden
Pharmaceuticals, have denied the allegations.
India
said earlier in December that tests on the four syrups showed that they
complied with specifications, and a government official told the BBC that the
WHO had been presumptuous in blaming the syrups. But the WHO said it stood by
the action taken.
Last week, a parliamentary committee in The Gambia
recommended the prosecution of Maiden Pharmaceuticals after weeks of
investigation. The committee also recommended banning all products by the firm
in the country.